
个人简介:
王佳敏,博士,副教授,硕士生导师,所属课题组:王建红课题组,邮箱:jmwang@henu.edu.cn,研究方向:诊疗一体化荧光探针的构建及生物成像应用、纸基荧光传感器的构建及在食品安全检测中的应用。
教育及工作经历:
(1)2016.07-至今,河南大学天然药物与免疫工程重点实验室,讲师、副教授
(2)2013.09-2016.07,中国科学院兰州化学物理研究所,博士
(3)2010.09-2013.07,中国科学院兰州化学物理研究所,硕士
(3)2006.09-2010.07,河北师范大学,学士
主持科研项目:
(1)河南省重点研发与推广专项(科技攻关),222102310692,在研,主持
(2)河南省重点研发与推广专项(科技攻关),212102310870,在研,主持
(3)河南省高等学校重点科研项目计划,18A150003,结题,主持
发表论文(任职河大以来):
(1) Nannan Wang, Xiaoyan Lu, Jiamin Wang,* Han Wang, Bo Zhang, Weili Zhao,* Jian Zhang,* Quasi-LDs-targeted and ONOO‒-responsive fluorescent probe for investigating the interaction of nonalcoholic fatty liver with drug-induced liver injury, Analytical Chemistry, accepted.
(2) Xiaokun Yang, Jiamin Wang,* Zunlong Zhang, Bo Zhang, Xiaolin Du, Jian Zhang,* Jianhong Wang,* BODIPY-based fluorescent probe for cysteine detection and its applications in food analysis, test strips and biological imaging, Food Chemistry, 2023, 416, 135730.
(3) Xiaokun Yang, Xiaoyan Lu, Jiamin Wang,* Zunlong Zhang, Xiaolin Du, Jian Zhang,* Jianhong Wang*, Near-Infrared fluorescent probe with a large stokes shift for detection of hydrogen sulfide in food spoilage, living cells, and zebrafish, Journal of Agricultural and Food Chemistry, 2022, 70, 3047-3055.
(4) Xiaoyan Lu, Nannan Wang, Yuanfang Tao, Jiamin Wang,* Xin Ji, Jinying Liu, Weili Zhao,* Jian Zhang*, Optimizing phenyl selenide-based BODIPYs as fluorescent probes for diagnosing cancer and drug-induced liver injury via cysteine, Chemical Communication, 2022, 58, 12576-12579.
(5) Nannan Wang, Han Wang, Jian Zhang,* Xin Ji, Huihui Su, Jinying Liu, Jiamin Wang,* Weili Zhao*, Diketopyrrolopyrrole-based sensor for over-expressed peroxynitrite in drug-induced hepatotoxicity via ratiometric fluorescence imaging, Sensors and Actuators: B. Chemical, 2022, 352, 130992.
(6) Nannan Wang, Han Wang, Jian Zhang,* Xin Ji, Huihui Su, Jinying Liu, Jiamin Wang,* Weili Zhao*, Endogenous peroxynitrite activated fluorescent probe for revealing anti-tuberculosis drug induced hepatotoxicity, Chinese Chemical Letters, 2022, 33, 1584-1588.
(7) Han Wang, Huihui Su, Nannan Wang, Jiamin Wang,* Jian Zhang,* Jianhong Wang,* Weili Zhao*, Recent development of reactional small-molecule fluorescent probes based on resorufin, Dyes and Pigments, 2021, 191, 109351.
(8) Jinlei Yue, Nannan Wang, Jiamin Wang,* Yuanfang Tao, Han Wang, Jinying Liu, Jian Zhang, Junrong Jiao,* Weili Zhao*, Three asymmetric BODIPY derivatives as fluorescent probes for highly selective and sensitive detection of cysteine in living cells, Analytical Methods, 2021, 13, 2908-2914.
(9) Huihui Su, Nannan Wang, Jiamin Wang,* Han Wang, Jian Zhang,* Weili Zhao,* A resorufin-based red-emitting fluorescent probe with high selectivity for tracking endogenous peroxynitrite in living cells and inflammatory mice, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 252, 119502.
(10) Linqiang Niu, Yang Luo, Haoran Zhao, Qijuan Cao, Jiamin Wang,* Jianhong Wang*, Hemicyanine-based fluorescent probe for distinguishing cysteine in living HeLa cells, Analytical Letters, 2021, 54, 2666-2675.
(11) Jian Zhang, Nannan Wang, Xin Ji, Yuanfang Tao, Jiamin Wang,* Weili Zhao,* BODIPY-based fluorescent probes for biothiols, Chemistry-A European Journal, 2020, 26, 4172-4192.
(12) Yuhui Men, Xiaomin Zhou, Zhijie Yan, Linqiang Niu, Yang Luo, Jiamin Wang,* Jianhong Wang,* A water-soluble near-infrared fluorescent probe for cysteine/homocysteine and its application in live cells and mice, Analytical Sciences, 2020, 36, 1053-1057.
(13) Jiamin Wang, Yuhui Men, Linqiang Niu, Yang Luo, Jian Zhang,* Weili Zhao, Jianhong Wang*, A reaction-based fluorescent probe for imaging of native hypochlorous acid, Chemistry- An Asian Journal, 2019, 14, 3893-3897.
(14) Xin Ji, Minghuan Lv, Fuchao Pan, Jian Zhang, Jianhong Wang, Jiamin Wang,* Weili Zhao*, A dual-response fluorescent probe for the discrimination of cysteine from glutathione and homocysteine, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 206, 1-7.
(15) Linqiang Niu, Jing Huang, Zhijie Yan, Yuhui Men, Yang Luo, Xiaomin Zhou, Jiamin Wang,* Jianhong Wang*, Fluorescence detection of intracellular pH changes in the mitochondria-associated process of mitophagy using a hemicyanine-based fluorescent probe, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 207, 123-131.
(16) Jiamin Wang,* Linqiang Niu, Jing Huang, Zhijie Yan, Jianhong Wang, A novel NBD-based fluorescent turn-on probe for the detection of cysteine and homocysteine in living cells, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 192, 52-58.
(17) Jiamin Wang,* Linqiang Niu, Jing Huang, Zhijie Yan, Xiaomin Zhou, Jianhong Wang*, Thiazolyl substituted NBD as fluorescent probe for the detection of homocysteine and cysteine, Dyes and Pigments, 2018, 158, 151-156.
(18) Jiamin Wang, Xiangmin Shao, Jianhong Wang,* Shijun Shao*, An NBD-based fluorescent turn-on probe for the detection of homocysteine over cysteine and its imaging applications, Chemistry Letters, 2017, 46, 442-445.
授权专利:
(1)王佳敏;张健;岳金磊;陶远芳;王瀚;王楠楠;苏慧慧;赵伟利;基于BODIPY染料靶向溶酶体选择性检测H2S的荧光探针、制备及应用,2021-10-1,中国,ZL 2020 1 1608723.1
(2)王佳敏;张健;苏慧慧;王瀚;王楠楠;陶远芳;岳金磊;赵伟利;基于试卤灵染料专一响应ONOO‒的荧光探针、制备方法及应用,2021-8-27,中国,ZL 2020 1 1330335.1
科研奖励:
(1)2019年开封市第十五届自然科学优秀学术成果奖二等奖。
(2)2021年开封市第十七届自然科学优秀学术成果奖三等奖。
(3)2022年河南大学优秀研究生指导教师。