天然药物与免疫工程重点实验室
设为首页  |  加入收藏
 
 网站首页  实验室概况  师资力量  学科建设  科学研究  人才招聘  实验室动态  研究生培养  下载中心  学术会议 
师资力量
 赵瑾 
 王超杰 
 姬汴生 
 江智勇 
 石家华 
 王建红 
 汪游清 
 赵美霞 
 张杰 
 张亚宏 
 岑娟 
 罗稳 
 刘洪均 
 魏国 
 于树玲 
 齐建国 
 代付军 
 马凡怡 
 赵媛 
 王佳敏 
 甘莹 
 李骞 
 李景华 
 赵筱薇 
通知公告 更多
 
 
当前位置: 网站首页>>师资力量>>罗稳>>正文
罗稳
2017-03-06 18:42   审核人:

基本信息

罗稳(1983-),男,河南信阳人,博士,副教授,硕士生导师。

教育经历:

2008/09–2011/06,中山大学,药学院,药物化学,博士,导师:古练权,黄志纾

2005/09–2008/06,河南大学,化学化工学院,有机化学,硕士,导师:赵瑾,王超杰

2001/09–2005/06,河南大学,化学化工学院,材料化学,学士

研究方向:抗肿瘤、抗老年痴呆药物的设计、合成及评价

联系方式:E-mail:luowen83@163.com

发表论文

1.Wen Luo,Ting Wang,Chen Hong, Yacheng Yang,YingChen, Juan Cen*, Songqiang Xie,Chaojie Wang*, Design, synthesis and evaluation of 4-dimethylamine flavonoid derivatives as potential multifunctional anti-Alzheimer agents,Eur. J. Med. Chem.,2016,122,17-26.

2.Qian Li, Yangyang Zhai,Wen Luo*,Zixin Zhun, Xin Zhang, Songqiang Xie*, Chen Hong, Yuxia Wang, Yabin Su, Jin Zhao,Chaojie Wang*,Synthesis and biological properties of polyamine modifiedflavonoids as hepatocellular carcinoma inhibitors European Journal of Medicinal Chemistry 121 (2016) 110-119.

3.Wen Luo*,YingChen, Ting Wang,Chen Hong, Liping Chang, Congcong Chang, Yacheng Yang, Songqiang Xie,Chaojie Wang*, Design, synthesis and evaluation of novel 7-aminoalkyl-substituted flavonoid derivatives with improved cholinesterase inhibitory activities,Bioorg. Med. Chem.,2016,24(4):672-680.

4.Xin Zhang, Jiang Wang,Chen Hong,Wen Luo*,Chaojie Wang*, Design, synthesis and evaluation of genisteinpolyamine conjugates as multi-functional anti-Alzheimer agents,Acta Pharm. Sinica B,2015,5(1):67-73.

5.Chen Hong,Wen Luo*,Dong Yao,Ya-BinSu,Xin Zhang, Run-Guo Tian,andChao-Jie Wang*, Novel aromatic–polyamine conjugates as cholinesterase inhibitorswith notable selectivity toward butyrylcholinesterase,Bioorg. Med. Chem.,2014, 22(12): 3213-3219.

6.Wen Luo*, Ya-BinSu,Chen Hong,Run-Guo Tian, Jun-Jie YueandChao-Jie Wang*, Design, synthesis and evaluation of novel 4-dimethylamine flavonoidderivatives as potential multi-functional anti-Alzheimer agents. Bioorg. Med. Chem.,2013,21(23): 7275-7282.

7.Wen Luo, Yan-Ping Li, Lian-Quan Gu, and Zhi-Shu Huang*, Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation. Bioorg. Med. Chem.,2011, 19(2): 763-770.

8.Wen Luo, Yan-Ping Li, Lian-Quan Gu, and Zhi-Shu Huang*, Synthesis and Evaluation of Heterobivalent Tarcrine Derivatives as Multi-potent Anti-Alzheimer Agents. Eur. J. Med. Chem.,2011, 46(6): 2609-2616.

科研项目

1.金属离子可调控的PAT识别及DNA嵌入双靶向"多胺-药物"缀合物的设计、合成及抗肿瘤活性.国家自然科学基金青年基金.项目号: 21302041,经费: 25万元, 2014.1.-2016.12, 主持。

2."黄酮-多胺"缀合物的合成及抗阿尔茨海默症活性研究.人事部博士后科学基金.项目号: 2012M521391,经费: 5.0万元, 2012.7.-2014.7,主持。

3."类黄酮-多胺"缀合物库的构建及其抗阿尔茨海默症活性评价.河南省教育厅科学技术研究重点项目.项目号: 14A350008,经费: 2.0万元, 2014.1.-2016.12. 主持。

授权专利

1.王超杰,罗稳,姚冬,赵永梅,含芳环结构的多胺衍生物及其制备方法和应用,河南大学,专利号:ZL 201210591736.1。

2.王超杰,罗稳,李骞,朱子新,翟洋洋,含黄酮结构的多胺衍生物及其制备方法和应用,河南大学,专利号:ZL 201310340647.4。

关闭窗口
 
 

版权所有:河南大学天然药物与免疫工程重点实验室 联系:0371-22864665